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Hepatocyte nuclear factor 1 alpha influences pancreatic cancer growth and metastasis

Hepatocyte nuclear factor 1 alpha influences pancreatic cancer growth and metastasis
Posted by Nicole

Hepatocyte nuclear issue 1 homeobox alpha (HNF1α) is a transcription issue concerned in endodermal organogenesis and pancreatic precursor cell differentiation and improvement. Earlier research have reported a task for HNF1α in pancreatic ductal adenocarcinoma (PDAC) however it’s controversial. The mechanism by which it impacts PDAC is but to be explored in depth. On this research, utilizing the web databases we noticed that HNF1α is upregulated in PDAC, which was additionally confirmed by our immunohistochemical evaluation of PDAC tissue microarray. Silencing HNF1α diminished the proliferative, migratory, invasive and colony forming capabilities of pancreatic most cancers cells. Key markers concerned in these processes (pPI3K, pAKT, pERK, Bcl2, Zeb, Snail, Slug) had been considerably modified in response to alterations in HNF1α expression. Alternatively, overexpression of HNF1α didn’t induce any important change within the aggressiveness of pancreatic most cancers cells. Our outcomes display that diminished expression of HNF1α results in inhibition of pancreatic most cancers development and development, which signifies that it might be a possible oncogene and goal for PDAC. The nucleoskeleton has been related to partitioning the genome into energetic and inactive compartments that dictate native transcription issue (TF) exercise. Nonetheless, current information point out that the nucleoskeleton and TFs reciprocally affect one another in dynamic TF trafficking pathways by means of the features of LEM proteins.

Whereas the conserved peripheral recruitment of TFs by LEM proteins has been seen as a mechanism of repressing transcription, a variety of launch mechanisms from the lamina counsel this compartment serves as a refuge for nuclear TF accumulation for speedy mobilization and sign stability. Detailed mechanisms counsel that TFs toggle between nuclear lamina refuge and nuclear matrix lamin-LEM protein complexes at websites of energetic transcription. On this evaluate we are going to spotlight rising LEM features appearing on the interface of chromatin and nucleoskeleton to create TF trafficking networks. Crohn’s illness (CD) is a continual inflammatory illness of unknown etiology that covers your entire digestive tract and happens with intervals of remission and scientific exacerbation. CD is commonest in North America and Europe, however its incidence is rising quickly in Asian nations. The pathogenesis of CD is unclear, whereas genetic predisposition, immune imbalance, and host-intestinal microbiota interactions are taken into consideration.

Incorrect activation of κB nuclear issue (NF-κB) signaling pathways is related to CD initiation and development. NF-κB results in extreme manufacturing of pro-inflammatory cytokines that trigger a continual inflammatory means of the intestines. It’s presently believed that the NF-κB pathway performs a key function within the pathogenesis of CD, therefore present remedies intention to dam this pathway. Research have proven that activation of NF-κB is diminished by remedy with, amongst others, mesalazine and glucocorticoids. This evaluate presents epidemiology and pathogenesis of CD, the participation of NF-κB on this illness, in addition to trendy strategies of remedy aimed toward inhibiting NF-κB activation.

 Hepatocyte nuclear factor 1 alpha influences pancreatic cancer growth and metastasis
Hepatocyte nuclear factor 1 alpha influences pancreatic cancer growth and metastasis

CD49d and CD49e induce cell adhesion-mediated drug resistance by means of the nuclear issue-κB pathway in Burkitt lymphoma

 

Burkitt lymphoma (BL) is a extremely aggressive type of non-Hodgkin’s B-cell lymphoma. At the moment, multi-agent chemotherapy regimens are getting used to considerably enhance treatment charges and obtain full remissions in BL sufferers. Nonetheless, drug resistance can typically happen inside 6 months in BL sufferers, contributing to poor prognosis. Mounting proof means that cell adhesion-mediated drug resistance (CAM-DR), brought on by the interplay between the bone marrow microenvironment and tumour cells could play an necessary function in drug resistance to chemotherapy. Nonetheless, the molecular mechanism underlying CAM-DR in BL has not been recognized but. On this research, we investigated the molecular mechanism accountable for CAM-DR in BL cells.

We additionally examined the therapeutic targets of CAM-DR in BL cells and located CD49d and CD49e to be the necessary adhesion molecules concerned. Nonetheless, CD49a, CD49b, CD11a, CD29, CD18, and CD61 weren’t discovered to be related to CAM-DR in BL cells. Moreover, we clarified that CD49d- and CD49e-mediated CAM-DR might be attributed to a rise within the expression of B cell leukemia-xL (Bcl-xL) and survivin proteins, and a lower within the expression of Bcl-2 related X (Bax), Bcl-2 interacting mediator (Bim) and p53 upregulated modulator of apoptosis (PUMA) proteins by way of nuclear issue kappaB (NF-κB) activation. As well as, bortezomib was discovered to beat CAM-DR in BL cells by inhibiting NF-κB. Thus, bortezomib could have potential scientific purposes within the remedy of CD49d- and CD49e-mediated CAM-DR in BL sufferers.

 

Diketoacetonylphenalenone, Derived from Hawaiian Volcanic Soil-Related Fungus Penicillium herquei FT729, Regulates T Cell Activation by way of Nuclear Issue-κB and Mitogen-Activated Protein Kinase Pathway

In immunological responses, controlling extreme T cell exercise is essential for immunological homeostasis upkeep. Diketoacetonylphenalenone, derived from Hawaiian volcanic soil-associated fungus Penicillium herquei FT729, possesses reasonable anti-inflammatory exercise in RAW 264.7 cells however its immunosuppressive impact on T cell activation is unknown. Within the current research, diketoacetonylphenalenone (as much as 40 μM) didn’t present cytotoxicity in T cells. Western blot evaluation confirmed remedy with diketoacetonylphenalenone didn’t alter the expression of anti-apoptotic proteins.

Inhibitory Subunit of NF Kappa B Zeta (IkBz) Antibody

20-abx103919
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Inhibitory Subunit of NF Kappa B Alpha (IkBa) Antibody

20-abx104016
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Inhibitory Subunit of NF Kappa B Delta (IkBd) Antibody

20-abx104017
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Inhibitory Subunit of NF Kappa B Epsilon (IkBe) Antibody

20-abx104115
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Antibody

20-abx172896
  • EUR 978.00
  • EUR 510.00
  • 1 mg
  • 200 ug

Inhibitory Subunit of NF Kappa B Beta (IkBb) Antibody

20-abx128815
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Inhibitory Subunit of NF Kappa B Epsilon (IkBe) Antibody

20-abx129779
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Inhibitory Subunit of NF Kappa B Delta (IkBd) Antibody

20-abx129839
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Antibody

20-abx176941
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Antibody

20-abx176942
  • EUR 1412.40
  • EUR 693.60
  • 1 mg
  • 200 ug

Recombinant Inhibitory Subunit Of NF Kappa B Alpha (IkBa)

4-RPB848Hu01
  • EUR 582.34
  • EUR 279.60
  • EUR 1853.76
  • EUR 697.92
  • EUR 1275.84
  • EUR 465.60
  • EUR 4454.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Inhibitory Subunit Of NF Kappa B Alpha expressed in: E.coli

Recombinant Inhibitory Subunit Of NF Kappa B Beta (IkBb)

4-RPB849Hu01
  • EUR 588.79
  • EUR 280.80
  • EUR 1877.95
  • EUR 705.98
  • EUR 1291.97
  • EUR 469.20
  • EUR 4514.88
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Inhibitory Subunit Of NF Kappa B Beta expressed in: E.coli

Recombinant Inhibitory Subunit Of NF Kappa B Beta (IkBb)

4-RPB849Mu01
  • EUR 588.79
  • EUR 280.80
  • EUR 1877.95
  • EUR 705.98
  • EUR 1291.97
  • EUR 469.20
  • EUR 4514.88
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Inhibitory Subunit Of NF Kappa B Beta expressed in: E.coli

Recombinant Inhibitory Subunit Of NF Kappa B Zeta (IkBz)

4-RPC249Hu01
  • EUR 593.09
  • EUR 282.00
  • EUR 1894.08
  • EUR 711.36
  • EUR 1302.72
  • EUR 472.80
  • EUR 4555.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Inhibitory Subunit Of NF Kappa B Zeta expressed in: E.coli

Recombinant Inhibitory Subunit Of NF Kappa B Zeta (IkBz)

4-RPC249Mu01
  • EUR 642.55
  • EUR 295.20
  • EUR 2079.55
  • EUR 773.18
  • EUR 1426.37
  • EUR 505.20
  • EUR 5018.88
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Inhibitory Subunit Of NF Kappa B Zeta expressed in: E.coli

Recombinant Inhibitory Subunit Of NF Kappa B Epsilon (IkBe)

4-RPE700Hu01
  • EUR 582.34
  • EUR 279.60
  • EUR 1853.76
  • EUR 697.92
  • EUR 1275.84
  • EUR 465.60
  • EUR 4454.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Inhibitory Subunit Of NF Kappa B Epsilon expressed in: E.coli

Recombinant Inhibitory Subunit Of NF Kappa B Epsilon (IkBe)

4-RPE700Mu01
  • EUR 599.54
  • EUR 283.20
  • EUR 1918.27
  • EUR 719.42
  • EUR 1318.85
  • EUR 476.40
  • EUR 4615.68
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Inhibitory Subunit Of NF Kappa B Epsilon expressed in: E.coli

Recombinant Inhibitory Subunit Of NF Kappa B Delta (IkBd)

4-RPE701Hu01
  • EUR 582.34
  • EUR 279.60
  • EUR 1853.76
  • EUR 697.92
  • EUR 1275.84
  • EUR 465.60
  • EUR 4454.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Inhibitory Subunit Of NF Kappa B Delta expressed in: E.coli

Recombinant Inhibitory Subunit Of NF Kappa B Delta (IkBd)

4-RPE701Mu01
  • EUR 614.59
  • EUR 288.00
  • EUR 1974.72
  • EUR 738.24
  • EUR 1356.48
  • EUR 487.20
  • EUR 4756.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Inhibitory Subunit Of NF Kappa B Delta expressed in: E.coli

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Protein

20-abx067213
  • EUR 811.20
  • EUR 343.20
  • EUR 2498.40
  • EUR 961.20
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Inhibitory Subunit Of NF Kappa B Beta (IkBb) Protein

20-abx067214
  • EUR 828.00
  • EUR 343.20
  • EUR 2532.00
  • EUR 978.00
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Inhibitory Subunit Of NF Kappa B Delta (IkBd) Protein

20-abx067215
  • EUR 811.20
  • EUR 343.20
  • EUR 2498.40
  • EUR 961.20
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Inhibitory Subunit Of NF Kappa B Epsilon (IkBe) Protein

20-abx067216
  • EUR 811.20
  • EUR 343.20
  • EUR 2498.40
  • EUR 961.20
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Inhibitory Subunit Of NF Kappa B Zeta (IkBz) Protein

20-abx067217
  • EUR 828.00
  • EUR 343.20
  • EUR 2548.80
  • EUR 978.00
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Inhibitory Subunit Of NF Kappa B Zeta (IkBz) Protein

20-abx067218
  • EUR 895.20
  • EUR 360.00
  • EUR 2798.40
  • EUR 1062.00
  • EUR 627.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Inhibitory Subunit Of NF Kappa B Delta (IkBd) Protein

20-abx168443
  • EUR 861.60
  • EUR 343.20
  • EUR 2665.20
  • EUR 1028.40
  • EUR 610.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Inhibitory Subunit Of NF Kappa B Beta (IkBb) Protein

20-abx166923
  • EUR 828.00
  • EUR 343.20
  • EUR 2532.00
  • EUR 978.00
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Inhibitory Subunit Of NF Kappa B Epsilon (IkBe) Protein

20-abx167376
  • EUR 844.80
  • EUR 343.20
  • EUR 2581.20
  • EUR 994.80
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Inhibitory Subunit of NF Kappa B Alpha (IkBa) Antibody Pair

20-abx370356
  • EUR 1996.80
  • EUR 1279.20
  • 10 × 96 tests
  • 5 × 96 tests

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Protein

20-abx653830
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Protein

20-abx653831
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Inhibitory Subunit of NF Kappa B Alpha (IkBa) Antibody (Biotin)

20-abx272200
  • EUR 526.80
  • EUR 292.80
  • EUR 1513.20
  • EUR 727.20
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

DLR-IkBa-Hu-48T 48T
EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

DLR-IkBa-Hu-96T 96T
EUR 776.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

DLR-IkBa-Mu-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

DLR-IkBa-Mu-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Inhibitory Subunit of NF Kappa B Alpha (IκBa) CLIA Kit

abx197166-96tests 96 tests
EUR 990

Inhibitory Subunit Of NF Kappa B Zeta (IkBz) Polyclonal Antibody (Human)

4-PAC249Hu01
  • EUR 296.40
  • EUR 3012.00
  • EUR 750.00
  • EUR 372.00
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Zeta (IkBz)

Inhibitory Subunit Of NF Kappa B Zeta (IkBz) Polyclonal Antibody (Mouse)

4-PAC249Mu01
  • EUR 301.20
  • EUR 3091.20
  • EUR 768.00
  • EUR 379.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Inhibitory Subunit Of NF Kappa B Zeta (IkBz)

Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Polyclonal Antibody (Human)

4-PAB848Hu01
  • EUR 286.80
  • EUR 2869.20
  • EUR 717.60
  • EUR 358.80
  • EUR 253.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa)

Inhibitory Subunit Of NF Kappa B Beta (IkBb) Polyclonal Antibody (Human)

4-PAB849Hu01
  • EUR 286.80
  • EUR 2869.20
  • EUR 717.60
  • EUR 358.80
  • EUR 253.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Beta (IkBb)

Inhibitory Subunit Of NF Kappa B Beta (IkBb) Polyclonal Antibody (Human)

4-PAB849Mu01
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Beta (IkBb)

Inhibitory Subunit Of NF Kappa B Epsilon (IkBe) Polyclonal Antibody (Human)

4-PAE700Hu01
  • EUR 296.40
  • EUR 3012.00
  • EUR 750.00
  • EUR 372.00
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Epsilon (IkBe)

Inhibitory Subunit Of NF Kappa B Epsilon (IkBe) Polyclonal Antibody (Mouse)

4-PAE700Mu01
  • EUR 301.20
  • EUR 3091.20
  • EUR 768.00
  • EUR 379.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Inhibitory Subunit Of NF Kappa B Epsilon (IkBe)

Inhibitory Subunit Of NF Kappa B Delta (IkBd) Polyclonal Antibody (Mouse)

4-PAE701Mu01
  • EUR 301.20
  • EUR 3091.20
  • EUR 768.00
  • EUR 379.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Inhibitory Subunit Of NF Kappa B Delta (IkBd)

Rat Inhibitory Subunit Of NF Kappa B Beta(IkBb)ELISA kit

QY-E10272 96T
EUR 433.2

Rat Inhibitory Subunit Of NF Kappa B Alpha(IkBa)ELISA kit

QY-E10273 96T
EUR 433.2

Mouse Inhibitory Subunit Of NF Kappa B Alpha(IkBa)ELISA kit

QY-E20792 96T
EUR 433.2

Mouse Inhibitory Subunit Of NF Kappa B Beta(IkBb)ELISA kit

QY-E20793 96T
EUR 433.2

Human Inhibitory Subunit Of NF Kappa B Beta(IkBb)ELISA Kit

QY-E03140 96T
EUR 433.2

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RD-IkBa-Hu-48Tests 48 Tests
EUR 600

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RD-IkBa-Hu-96Tests 96 Tests
EUR 830.4

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RD-IkBa-Mu-48Tests 48 Tests
EUR 613.2

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RD-IkBa-Mu-96Tests 96 Tests
EUR 850.8

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RDR-IkBa-Hu-48Tests 48 Tests
EUR 626.4

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RDR-IkBa-Hu-96Tests 96 Tests
EUR 868.8

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RDR-IkBa-Mu-48Tests 48 Tests
EUR 640.8

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RDR-IkBa-Mu-96Tests 96 Tests
EUR 890.4

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

SEB848Hu-10x96wellstestplate 10x96-wells test plate
EUR 5402.92
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

SEB848Hu-1x48wellstestplate 1x48-wells test plate
EUR 550.13
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

SEB848Hu-1x96wellstestplate 1x96-wells test plate
EUR 734.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

SEB848Hu-5x96wellstestplate 5x96-wells test plate
EUR 2945.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

4-SEB848Hu
  • EUR 5463.60
  • EUR 2886.00
  • EUR 735.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

SEB848Mu-10x96wellstestplate 10x96-wells test plate
EUR 5552.14
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

SEB848Mu-1x48wellstestplate 1x48-wells test plate
EUR 562.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

SEB848Mu-1x96wellstestplate 1x96-wells test plate
EUR 752.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

SEB848Mu-5x96wellstestplate 5x96-wells test plate
EUR 3024.07
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

4-SEB848Mu
  • EUR 5612.40
  • EUR 2965.20
  • EUR 752.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in samples from Tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Human Inhibitory Subunit Of NF Kappa B Alpha ELISA Kit (IkBa)

RK01651 96 Tests
EUR 625.2

ELISA kit for Human I?B? (Inhibitory Subunit of NF Kappa B Alpha)

E-EL-H2407 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Human I?B? (Inhibitory Subunit of NF Kappa B Alpha) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human I?B? (Inhibitory Subunit of NF Kappa B Beta)

E-EL-H2408 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Human I?B? (Inhibitory Subunit of NF Kappa B Beta) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Mouse I?B? (Inhibitory Subunit of NF Kappa B Alpha)

E-EL-M0863 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Mouse I?B? (Inhibitory Subunit of NF Kappa B Alpha) in samples from Serum, Plasma, Cell supernatant

CLIA kit for Human I?B? (Inhibitory Subunit of NF Kappa B Alpha)

E-CL-H1412 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Human I?B? (Inhibitory Subunit of NF Kappa B Alpha) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human IkBa (Inhibitory Subunit Of NF Kappa B Alpha)

ELK2219 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Inhibitory Subunit Of NF Kappa B Alpha from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Mouse IkBa (Inhibitory Subunit Of NF Kappa B Alpha)

ELK4340 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Inhibitory Subunit Of NF Kappa B Alpha from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Mouse Phospho-Inhibitory Subunit of NF Kappa B Alpha (NFKB1) ELISA Kit

abx352927-96tests 96 tests
EUR 943.2

Rabbit Phospho-Inhibitory Subunit Of NF Kappa B Alpha (NFKB1) ELISA Kit

abx363454-96tests 96 tests
EUR 990

Sheep Phospho-Inhibitory Subunit Of NF Kappa B Alpha (NFKB1) ELISA Kit

abx364407-96tests 96 tests
EUR 1111.2

Monkey Phospho-Inhibitory Subunit Of NF Kappa B Alpha (NFKB1) ELISA Kit

abx358780-96tests 96 tests
EUR 990

Pig Phospho-Inhibitory Subunit Of NF Kappa B Alpha (NFKB1) ELISA Kit

abx360538-96tests 96 tests
EUR 990

Human Phospho-Inhibitory Subunit of NF Kappa B Alpha (NFKB1) ELISA Kit

abx252966-96tests 96 tests
EUR 848.4

Rat Phospho-Inhibitory Subunit of NF Kappa B Alpha (NFKB1) ELISA Kit

abx255930-96tests 96 tests
EUR 848.4

Chicken Phospho-Inhibitory Subunit Of NF Kappa B Alpha (NFKB1) ELISA Kit

abx250077-96tests 96 tests
EUR 990

Inhibitory Subunit Of NF Kappa B Zeta (IkBz) Polyclonal Antibody (Human), APC

4-PAC249Hu01-APC
  • EUR 414.00
  • EUR 3930.00
  • EUR 1094.40
  • EUR 528.00
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Zeta (IkBz). This antibody is labeled with APC.

Inhibitory Subunit Of NF Kappa B Zeta (IkBz) Polyclonal Antibody (Human), Biotinylated

4-PAC249Hu01-Biotin
  • EUR 373.20
  • EUR 2952.00
  • EUR 872.40
  • EUR 457.20
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Zeta (IkBz). This antibody is labeled with Biotin.

Inhibitory Subunit Of NF Kappa B Zeta (IkBz) Polyclonal Antibody (Human), Cy3

4-PAC249Hu01-Cy3
  • EUR 502.80
  • EUR 5190.00
  • EUR 1410.00
  • EUR 654.00
  • EUR 301.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Zeta (IkBz). This antibody is labeled with Cy3.

Inhibitory Subunit Of NF Kappa B Zeta (IkBz) Polyclonal Antibody (Human), FITC

4-PAC249Hu01-FITC
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Zeta (IkBz). This antibody is labeled with FITC.

Inhibitory Subunit Of NF Kappa B Zeta (IkBz) Polyclonal Antibody (Human), HRP

4-PAC249Hu01-HRP
  • EUR 379.20
  • EUR 3426.00
  • EUR 968.40
  • EUR 477.60
  • EUR 247.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Zeta (IkBz). This antibody is labeled with HRP.

Inhibitory Subunit Of NF Kappa B Zeta (IkBz) Polyclonal Antibody (Human), PE

4-PAC249Hu01-PE
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Zeta (IkBz). This antibody is labeled with PE.

Inhibitory Subunit Of NF Kappa B Zeta (IkBz) Polyclonal Antibody (Mouse), APC

4-PAC249Mu01-APC
  • EUR 421.20
  • EUR 4038.00
  • EUR 1122.00
  • EUR 538.80
  • EUR 266.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Inhibitory Subunit Of NF Kappa B Zeta (IkBz). This antibody is labeled with APC.

Inhibitory Subunit Of NF Kappa B Zeta (IkBz) Polyclonal Antibody (Mouse), Biotinylated

4-PAC249Mu01-Biotin
  • EUR 379.20
  • EUR 3031.20
  • EUR 892.80
  • EUR 464.40
  • EUR 265.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Inhibitory Subunit Of NF Kappa B Zeta (IkBz). This antibody is labeled with Biotin.

Inhibitory Subunit Of NF Kappa B Zeta (IkBz) Polyclonal Antibody (Mouse), Cy3

4-PAC249Mu01-Cy3
  • EUR 512.40
  • EUR 5334.00
  • EUR 1446.00
  • EUR 668.40
  • EUR 304.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Inhibitory Subunit Of NF Kappa B Zeta (IkBz). This antibody is labeled with Cy3.

Inhibitory Subunit Of NF Kappa B Zeta (IkBz) Polyclonal Antibody (Mouse), FITC

4-PAC249Mu01-FITC
  • EUR 361.20
  • EUR 3254.40
  • EUR 921.60
  • EUR 454.80
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Inhibitory Subunit Of NF Kappa B Zeta (IkBz). This antibody is labeled with FITC.

Inhibitory Subunit Of NF Kappa B Zeta (IkBz) Polyclonal Antibody (Mouse), HRP

4-PAC249Mu01-HRP
  • EUR 385.20
  • EUR 3519.60
  • EUR 992.40
  • EUR 486.00
  • EUR 250.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Inhibitory Subunit Of NF Kappa B Zeta (IkBz). This antibody is labeled with HRP.

Inhibitory Subunit Of NF Kappa B Zeta (IkBz) Polyclonal Antibody (Mouse), PE

4-PAC249Mu01-PE
  • EUR 361.20
  • EUR 3254.40
  • EUR 921.60
  • EUR 454.80
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Inhibitory Subunit Of NF Kappa B Zeta (IkBz). This antibody is labeled with PE.

Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Polyclonal Antibody (Human), APC

4-PAB848Hu01-APC
  • EUR 399.60
  • EUR 3735.60
  • EUR 1046.40
  • EUR 507.60
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa). This antibody is labeled with APC.

Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Polyclonal Antibody (Human), Biotinylated

4-PAB848Hu01-Biotin
  • EUR 363.60
  • EUR 2809.20
  • EUR 836.40
  • EUR 442.80
  • EUR 259.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa). This antibody is labeled with Biotin.

Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Polyclonal Antibody (Human), Cy3

4-PAB848Hu01-Cy3
  • EUR 483.60
  • EUR 4930.80
  • EUR 1345.20
  • EUR 627.60
  • EUR 294.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa). This antibody is labeled with Cy3.

Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Polyclonal Antibody (Human), FITC

4-PAB848Hu01-FITC
  • EUR 344.40
  • EUR 3012.00
  • EUR 860.40
  • EUR 430.80
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa). This antibody is labeled with FITC.

Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Polyclonal Antibody (Human), HRP

4-PAB848Hu01-HRP
  • EUR 366.00
  • EUR 3256.80
  • EUR 926.40
  • EUR 459.60
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa). This antibody is labeled with HRP.

Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Polyclonal Antibody (Human), PE

4-PAB848Hu01-PE
  • EUR 344.40
  • EUR 3012.00
  • EUR 860.40
  • EUR 430.80
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa). This antibody is labeled with PE.

Inhibitory Subunit Of NF Kappa B Beta (IkBb) Polyclonal Antibody (Human), APC

4-PAB849Hu01-APC
  • EUR 399.60
  • EUR 3735.60
  • EUR 1046.40
  • EUR 507.60
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Beta (IkBb). This antibody is labeled with APC.

Inhibitory Subunit Of NF Kappa B Beta (IkBb) Polyclonal Antibody (Human), Biotinylated

4-PAB849Hu01-Biotin
  • EUR 363.60
  • EUR 2809.20
  • EUR 836.40
  • EUR 442.80
  • EUR 259.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Beta (IkBb). This antibody is labeled with Biotin.

Inhibitory Subunit Of NF Kappa B Beta (IkBb) Polyclonal Antibody (Human), Cy3

4-PAB849Hu01-Cy3
  • EUR 483.60
  • EUR 4930.80
  • EUR 1345.20
  • EUR 627.60
  • EUR 294.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Beta (IkBb). This antibody is labeled with Cy3.

Inhibitory Subunit Of NF Kappa B Beta (IkBb) Polyclonal Antibody (Human), FITC

4-PAB849Hu01-FITC
  • EUR 344.40
  • EUR 3012.00
  • EUR 860.40
  • EUR 430.80
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Beta (IkBb). This antibody is labeled with FITC.

Inhibitory Subunit Of NF Kappa B Beta (IkBb) Polyclonal Antibody (Human), HRP

4-PAB849Hu01-HRP
  • EUR 366.00
  • EUR 3256.80
  • EUR 926.40
  • EUR 459.60
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Beta (IkBb). This antibody is labeled with HRP.

Inhibitory Subunit Of NF Kappa B Beta (IkBb) Polyclonal Antibody (Human), PE

4-PAB849Hu01-PE
  • EUR 344.40
  • EUR 3012.00
  • EUR 860.40
  • EUR 430.80
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Beta (IkBb). This antibody is labeled with PE.

Inhibitory Subunit Of NF Kappa B Beta (IkBb) Polyclonal Antibody (Human), APC

4-PAB849Mu01-APC
  • EUR 408.00
  • EUR 3843.60
  • EUR 1072.80
  • EUR 518.40
  • EUR 260.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Beta (IkBb). This antibody is labeled with APC.

Inhibitory Subunit Of NF Kappa B Beta (IkBb) Polyclonal Antibody (Human), Biotinylated

4-PAB849Mu01-Biotin
  • EUR 368.40
  • EUR 2888.40
  • EUR 856.80
  • EUR 450.00
  • EUR 260.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Beta (IkBb). This antibody is labeled with Biotin.

Inhibitory Subunit Of NF Kappa B Beta (IkBb) Polyclonal Antibody (Human), Cy3

4-PAB849Mu01-Cy3
  • EUR 493.20
  • EUR 5074.80
  • EUR 1381.20
  • EUR 642.00
  • EUR 297.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Beta (IkBb). This antibody is labeled with Cy3.

Inhibitory Subunit Of NF Kappa B Beta (IkBb) Polyclonal Antibody (Human), FITC

4-PAB849Mu01-FITC
  • EUR 350.40
  • EUR 3098.40
  • EUR 882.00
  • EUR 439.20
  • EUR 232.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Beta (IkBb). This antibody is labeled with FITC.

Inhibitory Subunit Of NF Kappa B Beta (IkBb) Polyclonal Antibody (Human), HRP

4-PAB849Mu01-HRP
  • EUR 373.20
  • EUR 3350.40
  • EUR 949.20
  • EUR 469.20
  • EUR 246.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Beta (IkBb). This antibody is labeled with HRP.

Inhibitory Subunit Of NF Kappa B Beta (IkBb) Polyclonal Antibody (Human), PE

4-PAB849Mu01-PE
  • EUR 350.40
  • EUR 3098.40
  • EUR 882.00
  • EUR 439.20
  • EUR 232.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Beta (IkBb). This antibody is labeled with PE.

Inhibitory Subunit Of NF Kappa B Epsilon (IkBe) Polyclonal Antibody (Human), APC

4-PAE700Hu01-APC
  • EUR 414.00
  • EUR 3930.00
  • EUR 1094.40
  • EUR 528.00
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Inhibitory Subunit Of NF Kappa B Epsilon (IkBe). This antibody is labeled with APC.
Pretreatment with diketoacetonylphenalenone suppressed the interleukin-2 manufacturing in activated T cells induced by T cell receptor-mediated stimulation and PMA/A23187. The CFSE-proliferation assay revealed the inhibitory impact of diketoacetonylphenalenone on the proliferation of T cells. The expression of floor molecules on activated T cells was additionally diminished. We found the suppression of the TAK1-IKKα-NF-κB pathway by pretreatment with diketoacetonylphenalenone abrogated mitogen-activated protein kinase (MAPK) signaling in activated T cells. These outcomes counsel that diketoacetonylphenalenone successfully downregulates T cell exercise by way of the MAPK pathway and gives perception into the therapeutic potential of immunosuppressive reagents.

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