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Transcriptional Regulation of the Angptl8 Gene by Hepatocyte Nuclear Issue-1 within the Murine Liver
Temporary refeeding instances (~60 min) enhanced hepatic Angptl8 expression in fasted mice. We cloned the mouse Angptl8 promoter area to characterise this speedy refeeding-induced enhance in hepatic Angptl8 expression. Deletion of the -309/-60 promoter area considerably attenuated basal promoter exercise in hepatocytes.
A computational motif search revealed a possible binding motif for hepatocyte nuclear issue 1α/1β (HNF-1α/β) at -84/-68 bp of the promoter. Mutation of the HNF-1 binding web site considerably decreased the promoter exercise in hepatocytes, and the promoter carrying the mutated HNF-1 web site was not transactivated by co-transfection of HNF-1 in a non-hepatic cell line. Silencing Hnf-1 in hepatoma cells and mouse main hepatocytes decreased Angptl8 protein ranges.
Electrophoretic mobility-shift assays confirmed direct binding of Hnf-1 to its Angptl8 promoter binding motif. Hnf-1α expression ranges elevated after short-term refeeding, paralleling the improved in vivo expression of the Angptl8 protein. Chromatin immunoprecipitation (ChIP) confirmed the recruitment of endogenous Hnf-1 to the Angptl8 promoter area.
Nuclear respiratory issue 1 (NRF-1) upregulates the expression and performance of decreased folate provider (RFC) on the blood-brain barrier
Folates are vital for neurodevelopment and cognitive perform. Folate transport throughout organic membranes is mediated by three main pathways: folate receptor alpha (FRα), proton-coupled folate transporter (PCFT), and decreased folate provider (RFC).
Mind folate transport primarily happens on the choroid plexus by FRα and PCFT; inactivation of those transport techniques leads to suboptimal folate ranges within the cerebrospinal fluid (CSF) inflicting childhood neurological problems.
Anti-Development hormone receptor (3A12) |
Our group has reported that upregulation of RFC on the blood-brain barrier (BBB) by interactions with particular transcription components, that’s, vitamin D receptor (VDR) might enhance mind folate supply. This research investigates the position of nuclear respiratory issue 1 (NRF-1) within the regulation of RFC on the BBB. Activation of NRF-1/PGC-1α signaling by remedy with its particular ligand, pyrroloquinoline quinone (PQQ), considerably induced RFC expression and transport exercise in hCMEC/D3 cells.
In distinction, transfection with NRF-1 or PGC-1α focusing on siRNA downregulated RFC purposeful expression in the identical cell system. Making use of chromatin immunoprecipitation (ChIP) assay, we additional demonstrated that PQQ remedy elevated NRF-1 binding to putative NRF-1 binding websites throughout the SLC19A1 promoter, which encodes for RFC.
Moreover, in vivo remedy of untamed sort mice with PQQ-induced RFC expression in remoted mouse mind capillaries. Collectively, these findings show that NRF-1/PGC-1α activation by PQQ upregulates RFC purposeful expression on the BBB and will probably improve mind folate uptake.
Anti-Tryptophanyl tRNA synthetase (3A12) |
Insulin-treated main hepatocytes confirmed elevated expression of Angptl8 protein, however knockdown of Hnf-1 fully abolished this enhancement. HNF-1 seems to play important roles within the speedy refeeding-induced will increase in Angptl8 expression. HNF-1α could due to this fact characterize a main medical goal for ANGPTL8-related metabolic abnormalities. The research revealed the transcriptional regulation of the mouse hepatic Angptl8 gene by HNF-1.
Monoclonal PARP Antibody (Clone 7A10), Clone: 7A10 |
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| APR08931G | Leading Biology | 0.1ml | EUR 633.6 |
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Description: A Monoclonal antibody against Human PARP (Clone 7A10). The antibodies are raised in Mouse and are from clone 7A10. This antibody is applicable in WB, FC, ICC |
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Monoclonal PHF7 Antibody (clone 1A11), Clone: 1A11 |
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| APR17842G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human PHF7 (clone 1A11). The antibodies are raised in Mouse and are from clone 1A11. This antibody is applicable in WB and IHC-P, IF, Flo |
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Monoclonal HDAC1 Antibody (clone 5A11), Clone: 5A11 |
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| AMM02093G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human HDAC1 (clone 5A11). The antibodies are raised in Mouse and are from clone 5A11. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal TNFRSF10A / DR4 Antibody (clone 32A1380), Clone: 32A1380 |
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| AMM01748G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human TNFRSF10A / DR4 (clone 32A1380). The antibodies are raised in Mouse and are from clone 32A1380. This antibody is applicable in WB and IHC-P, Neut, Flo |
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Monoclonal TNFRSF10A / DR4 Antibody (clone 32A242), Clone: 32A242 |
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| AMM01749G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human TNFRSF10A / DR4 (clone 32A242). The antibodies are raised in Mouse and are from clone 32A242. This antibody is applicable in WB and IHC-P |
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Monoclonal Vimentin Antibody (clone 2A52), Clone: 2A52 |
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| AMM02306G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human Vimentin (clone 2A52). The antibodies are raised in Mouse and are from clone 2A52. This antibody is applicable in WB and IHC-P, IF, ICC |
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Monoclonal AMACR Antibody (clone 2A10F3), Clone: 2A10F3 |
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| APG01846G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human AMACR (clone 2A10F3). The antibodies are raised in Mouse and are from clone 2A10F3. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal SYN / FYN Antibody (clone 2A10), Clone: 2A10 |
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| AMM02294G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human SYN / FYN (clone 2A10). The antibodies are raised in Mouse and are from clone 2A10. This antibody is applicable in WB and IHC-P, IF, ICC, E, Flo |
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Monoclonal NFkB p65 Antibody (Clone 2A12A7), Clone: 2A12A7 |
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| AMM00002G | Leading Biology | 0.1mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human NFkB p65 (Clone 2A12A7). The antibodies are raised in Mouse and are from clone 2A12A7. This antibody is applicable in WB and IHC, IP |
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Monoclonal TLR2 Antibody (Extracellular Domain, clone 1030A5.138), Clone: 1030A5.138 |
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| APR11211G | Leading Biology | 0.1ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human TLR2 (Extracellular Domain, clone 1030A5.138). The antibodies are raised in Mouse and are from clone 1030A5.138. This antibody is applicable in WB and IHC-P, Flo |
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Monoclonal TRAF2 Antibody (aa205-222, clone 33A1293), Clone: 33A1293 |
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| AMM01751G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human TRAF2 (aa205-222, clone 33A1293). The antibodies are raised in Mouse and are from clone 33A1293. This antibody is applicable in WB and IHC-P |
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Monoclonal YAP / YAP1 Antibody (clone 1A12), Clone: 1A12 |
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| AMM02201G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human YAP / YAP1 (clone 1A12). The antibodies are raised in Mouse and are from clone 1A12. This antibody is applicable in WB and IHC-P, E, Flo |
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Monoclonal TRAF5 Antibody (aa77-186, clone 55A219), Clone: 55A219 |
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| AMM01752G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human TRAF5 (aa77-186, clone 55A219). The antibodies are raised in Mouse and are from clone 55A219. This antibody is applicable in WB and IHC-P |
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Monoclonal COPS5 / JAB1 Antibody (clone 2A10.8), Clone: 2A10.8 |
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| AMM01711G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human COPS5 / JAB1 (clone 2A10.8). The antibodies are raised in Mouse and are from clone 2A10.8. This antibody is applicable in WB and IHC-P, IF, IP |
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Monoclonal TLN1 / Talin Antibody (clone 1A11), Clone: 1A11 |
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| AMM08222G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human TLN1 / Talin (clone 1A11). The antibodies are raised in Mouse and are from clone 1A11. This antibody is applicable in WB and IHC-P, E |
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Monoclonal MEF2A / MEF2 Antibody (clone 1A10), Clone: 1A10 |
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| APR12521G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human MEF2A / MEF2 (clone 1A10). The antibodies are raised in Mouse and are from clone 1A10. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal ABCA1 Antibody (aa1800-2260, clone A00121.01), Clone: A00121.01 |
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| APG01394G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human ABCA1 (aa1800-2260, clone A00121.01). The antibodies are raised in Mouse and are from clone A00121.01. This antibody is applicable in WB and IHC-P, E |
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Monoclonal PTP1B Antibody (Clone 107AT531), Clone: 107AT531 |
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| AMR09648G | Leading Biology | 0.1mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human PTP1B (Clone 107AT531). The antibodies are raised in Mouse and are from clone 107AT531. This antibody is applicable in WB, E |
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Monoclonal ALDH1A1 / ALDH1 Antibody (clone 5A11), Clone: 5A11 |
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| AMM02227G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human ALDH1A1 / ALDH1 (clone 5A11). The antibodies are raised in Mouse and are from clone 5A11. This antibody is applicable in WB and IHC-P, E |
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Monoclonal Rhodopsin / RHO Antibody (clone A531), Clone: A531 |
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| APR13099G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human Rhodopsin / RHO (clone A531). The antibodies are raised in Mouse and are from clone A531. This antibody is applicable in WB and IHC, IHC-P, IF |
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Monoclonal NAK / TBK1 Antibody (aa563-577, clone 108A429), Clone: 108A429 |
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| APR17527G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human NAK / TBK1 (aa563-577, clone 108A429). The antibodies are raised in Mouse and are from clone 108A429. This antibody is applicable in WB and IHC-P |
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Monoclonal CD27 Antibody (clone LG.3A10), Clone: LG.3A10 |
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| AMH00003G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human CD27 (clone LG.3A10). The antibodies are raised in Hamster and are from clone LG.3A10. This antibody is applicable in IHC-P, E, IP, Flo |
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Monoclonal LMNA / Lamin A/C Antibody (clone 133A2), Clone: 133A2 |
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| AMM02262G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human LMNA / Lamin A/C (clone 133A2). The antibodies are raised in Mouse and are from clone 133A2. This antibody is applicable in WB and IHC-P, ICC, IHC-Fr, Flo |
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Monoclonal c-Kit / CD117 Antibody (clone 9A11), Clone: 9A11 |
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| AMM02228G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human c-Kit / CD117 (clone 9A11). The antibodies are raised in Mouse and are from clone 9A11. This antibody is applicable in WB and IHC-P |
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PGP9.5 (Clone: 31A3) |
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| MO25010 | Neuromics | 100 ul | EUR 804 |
Monoclonal PHGDH Antibody (clone 4A3-1D6), Clone: 4A3-1D6 |
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| APR09114G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human PHGDH (clone 4A3-1D6). The antibodies are raised in Mouse and are from clone 4A3-1D6. This antibody is applicable in WB and IHC-P, IF, E, IP |
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Monoclonal LC3 (APG8) Antibody (Clone 166AT1234), Clone: 166AT1234 |
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| APR08151G | Leading Biology | 0.1ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human LC3 (APG8) (Clone 166AT1234). The antibodies are raised in Mouse and are from clone 166AT1234. This antibody is applicable in WB, IHC and IF |
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Monoclonal SH3GLB1 / Bif / Endophilin B1 Antibody (clone 30A882.1.1), Clone: 30A882.1.1 |
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| APR09918G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human SH3GLB1 / Bif / Endophilin B1 (clone 30A882.1.1). The antibodies are raised in Mouse and are from clone 30A882.1.1. This antibody is applicable in WB and IHC-P |
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Monoclonal Osteoprotegerin / OPG Antibody (aa20-37, clone 98A1071), Clone: 98A1071 |
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| APR08890G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human Osteoprotegerin / OPG (aa20-37, clone 98A1071). The antibodies are raised in Mouse and are from clone 98A1071. This antibody is applicable in WB and IHC-P |
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Monoclonal Lysyl Oxidase / LOX Antibody (clone 9A11), Clone: 9A11 |
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| AMM02287G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human Lysyl Oxidase / LOX (clone 9A11). The antibodies are raised in Mouse and are from clone 9A11. This antibody is applicable in WB and IHC-P, IF, Flo |
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Monoclonal RTN3 / Reticulon 3 Antibody (clone 10A8), Clone: 10A8 |
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| AMR09784G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human RTN3 / Reticulon 3 (clone 10A8). The antibodies are raised in Mouse and are from clone 10A8. This antibody is applicable in IHC-P, E |
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Monoclonal HK1 / Hexokinase 1 Antibody (clone 3A10), Clone: 3A10 |
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| APR07755G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human HK1 / Hexokinase 1 (clone 3A10). The antibodies are raised in Mouse and are from clone 3A10. This antibody is applicable in WB and IHC-P, IF, ICC, E, Flo |
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Monoclonal VHL / Von Hippel Lindau Antibody (clone 52A11), Clone: 52A11 |
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| APR10722G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human VHL / Von Hippel Lindau (clone 52A11). The antibodies are raised in Mouse and are from clone 52A11. This antibody is applicable in WB and IHC-P, E |
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Monoclonal TNFRSF11A / RANK Antibody (aa326-616, clone 9A725), Clone: 9A725 |
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| APR13768G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human TNFRSF11A / RANK (aa326-616, clone 9A725). The antibodies are raised in Mouse and are from clone 9A725. This antibody is applicable in WB and IHC-P, Flo |
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Monoclonal S100B / S100 Beta Antibody (clone 9A11B9), Clone: 9A11B9 |
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| AMM01826G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human S100B / S100 Beta (clone 9A11B9). The antibodies are raised in Mouse and are from clone 9A11B9. This antibody is applicable in WB and IHC-P, E |
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Monoclonal CD27 Antibody (clone LG.3A10, FITC), Clone: LG.3A10 |
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| AMH00001G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human CD27 (clone LG.3A10, FITC). The antibodies are raised in Hamster and are from clone LG.3A10. This antibody is applicable in IHC-P, IHC-Fr, Flo |
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Monoclonal Nestin Antibody (clone 2C1.3A11), Clone: 2C1.3A11 |
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| AMM01780G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human Nestin (clone 2C1.3A11). The antibodies are raised in Mouse and are from clone 2C1.3A11. This antibody is applicable in WB and IHC-P, ICC, IP, Flo |
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Monoclonal EPHB3 / EPH Receptor B3 Antibody (clone 4A122D1), Clone: 4A122D1 |
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| AMM01871G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human EPHB3 / EPH Receptor B3 (clone 4A122D1). The antibodies are raised in Mouse and are from clone 4A122D1. This antibody is applicable in WB and IHC-P, E |
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Monoclonal C/EBP Beta / CEBPB Antibody (clone 47A1), Clone: 47A1 |
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| AMM01793G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human C/EBP Beta / CEBPB (clone 47A1). The antibodies are raised in Mouse and are from clone 47A1. This antibody is applicable in WB and IHC-P, E |
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Monoclonal VCP Antibody (clone 4A8), Clone: 4A8 |
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| APR10681G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human VCP (clone 4A8). The antibodies are raised in Mouse and are from clone 4A8. This antibody is applicable in WB and IHC-P, E |
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Monoclonal YY1 Antibody (clone 4A5), Clone: 4A5 |
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| APR14011G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human YY1 (clone 4A5). The antibodies are raised in Mouse and are from clone 4A5. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal PGD Antibody (clone 2A5), Clone: 2A5 |
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| APR09072G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human PGD (clone 2A5). The antibodies are raised in Mouse and are from clone 2A5. This antibody is applicable in WB and IHC-P, IF |
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Monoclonal BAX Antibody (clone 6A7), Clone: 6A7 |
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| APG02213G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human BAX (clone 6A7). The antibodies are raised in Mouse and are from clone 6A7. This antibody is applicable in WB and IHC-P, IP |
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Monoclonal CCS Antibody (clone 3A1), Clone: 3A1 |
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| APG02475G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human CCS (clone 3A1). The antibodies are raised in Mouse and are from clone 3A1. This antibody is applicable in WB and IHC-P, E, IP |
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Monoclonal KLK3 / PSA Antibody (aa26-251, clone 5A11E2), Clone: 5A11E2 |
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| AMM01829G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human KLK3 / PSA (aa26-251, clone 5A11E2). The antibodies are raised in Mouse and are from clone 5A11E2. This antibody is applicable in WB and IHC-P, E, Flo |
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Monoclonal CLU / Clusterin Antibody (aa1-333, clone 1A11), Clone: 1A11 |
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| APG02668G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human CLU / Clusterin (aa1-333, clone 1A11). The antibodies are raised in Mouse and are from clone 1A11. This antibody is applicable in WB and IHC-P, E |
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Monoclonal PLG / Plasmin / Plasminogen Antibody (clone 10A1), Clone: 10A1 |
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| AMM02175G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human PLG / Plasmin / Plasminogen (clone 10A1). The antibodies are raised in Mouse and are from clone 10A1. This antibody is applicable in WB and IHC-P, E |
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Monoclonal ART3 Antibody (clone 3A2), Clone: 3A2 |
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| AMM01902G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human ART3 (clone 3A2). The antibodies are raised in Mouse and are from clone 3A2. This antibody is applicable in WB and IHC-P, E |
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Monoclonal MDM2 Antibody (clone 1A7), Clone: 1A7 |
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| AMM02008G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human MDM2 (clone 1A7). The antibodies are raised in Mouse and are from clone 1A7. This antibody is applicable in WB and IHC-P, E |
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Monoclonal ATF2 Antibody (clone 4A3), Clone: 4A3 |
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| AMM02133G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human ATF2 (clone 4A3). The antibodies are raised in Mouse and are from clone 4A3. This antibody is applicable in WB and IHC-P, E |
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Monoclonal RRAS Antibody (clone 6A8), Clone: 6A8 |
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| AMM02147G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human RRAS (clone 6A8). The antibodies are raised in Mouse and are from clone 6A8. This antibody is applicable in WB and IHC-P |
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Monoclonal OCRL Antibody (clone 4A6), Clone: 4A6 |
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| APR17655G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human OCRL (clone 4A6). The antibodies are raised in Mouse and are from clone 4A6. This antibody is applicable in WB and IHC-P, E |
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Monoclonal CD80 Antibody (clone 2A2), Clone: 2A2 |
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| AMM05353G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human CD80 (clone 2A2). The antibodies are raised in Mouse and are from clone 2A2. This antibody is applicable in IHC-P, IF, E |
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Monoclonal TIMP2 Antibody (clone 3A4), Clone: 3A4 |
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| AMM01899G | Leading Biology | 0.1mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human TIMP2 (clone 3A4). The antibodies are raised in Mouse and are from clone 3A4. This antibody is applicable in WB and IHC-P, E |
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Monoclonal SMAD6 Antibody (clone 2A6), Clone: 2A6 |
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| AMM01921G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human SMAD6 (clone 2A6). The antibodies are raised in Mouse and are from clone 2A6. This antibody is applicable in WB and IHC-P, E |
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Monoclonal CXCL5 Antibody (clone 2A9), Clone: 2A9 |
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| AMM02029G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human CXCL5 (clone 2A9). The antibodies are raised in Mouse and are from clone 2A9. This antibody is applicable in WB and IHC-P, E |
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Monoclonal CD105 Antibody (clone 8A1), Clone: 8A1 |
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| AMM02219G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human CD105 (clone 8A1). The antibodies are raised in Mouse and are from clone 8A1. This antibody is applicable in WB and IHC-P, IF |
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Monoclonal VWA5A Antibody (clone 3A3), Clone: 3A3 |
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| AMM02304G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human VWA5A (clone 3A3). The antibodies are raised in Mouse and are from clone 3A3. This antibody is applicable in WB and IHC-P, IF, Flo |
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Monoclonal REG1A Antibody (clone 1A4), Clone: 1A4 |
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| AMR09710G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human REG1A (clone 1A4). The antibodies are raised in Mouse and are from clone 1A4. This antibody is applicable in IHC-P, IF, E |
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Monoclonal GMEB1 Antibody (clone 2A8), Clone: 2A8 |
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| APR11097G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human GMEB1 (clone 2A8). The antibodies are raised in Mouse and are from clone 2A8. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal HCLS1 Antibody (clone 2A8), Clone: 2A8 |
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| APR16675G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human HCLS1 (clone 2A8). The antibodies are raised in Mouse and are from clone 2A8. This antibody is applicable in WB and IHC-P, E |
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Monoclonal CAMK4 Antibody (clone 1A3), Clone: 1A3 |
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| APG03190G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human CAMK4 (clone 1A3). The antibodies are raised in Mouse and are from clone 1A3. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal PODXL Antibody [Clone 2A4], Clone: 2A4 |
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| AMM00040G | Leading Biology | 0.1mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human PODXL [Clone 2A4]. The antibodies are raised in Mouse and are from clone 2A4. This antibody is applicable in WB, IHC and IF, FC, IP |
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Monoclonal BPIFB1 Antibody (clone 2A5), Clone: 2A5 |
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| APR11011G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human BPIFB1 (clone 2A5). The antibodies are raised in Mouse and are from clone 2A5. This antibody is applicable in WB and IHC-P, IF, ICC, E, Flo |
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Monoclonal AKR1B10 Antibody (clone 1A6), Clone: 1A6 |
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| APG01656G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human AKR1B10 (clone 1A6). The antibodies are raised in Mouse and are from clone 1A6. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal ALDH1L1 Antibody (clone 2A6), Clone: 2A6 |
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| APG01736G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human ALDH1L1 (clone 2A6). The antibodies are raised in Mouse and are from clone 2A6. This antibody is applicable in WB and IHC-P, Flo |
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Monoclonal Glutathione Peroxidase 3 Antibody (Clone 55A), Clone: Clone 55A |
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| AMRa00027G | Leading Biology | 0.1ml | EUR 633.6 |
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Description: A Monoclonal antibody against Human Glutathione Peroxidase 3 (Clone 55A). The antibodies are raised in Mouse and are from clone Clone 55A. This antibody is applicable in E, IP |
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Monoclonal MYL4 Antibody (aa2-197, clone 5A2), Clone: 5A2 |
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| AMM02313G | Leading Biology | 0.05ml | EUR 580.8 |
|
Description: A Monoclonal antibody against Human MYL4 (aa2-197, clone 5A2). The antibodies are raised in Mouse and are from clone 5A2. This antibody is applicable in WB and IHC-P |
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Monoclonal CACNA2D2 Antibody (clone 3A4), Clone: 3A4 |
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| AMM05669G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human CACNA2D2 (clone 3A4). The antibodies are raised in Mouse and are from clone 3A4. This antibody is applicable in WB and IHC-P, E |
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Monoclonal BAIAP2L1 Antibody (clone 2A4), Clone: 2A4 |
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| APR15127G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human BAIAP2L1 (clone 2A4). The antibodies are raised in Mouse and are from clone 2A4. This antibody is applicable in WB and IHC-P, E |
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Monoclonal ATP6V1B2 Antibody (clone 2A5), Clone: 2A5 |
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| APG02143G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human ATP6V1B2 (clone 2A5). The antibodies are raised in Mouse and are from clone 2A5. This antibody is applicable in WB and IHC-P, E |
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Monoclonal IL13 Antibody (clone A130D 12G5 1E4), Clone: A130D 12G5 1E4 |
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| AMM01848G | Leading Biology | 10.05mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human IL13 (clone A130D 12G5 1E4). The antibodies are raised in Mouse and are from clone A130D 12G5 1E4. This antibody is applicable in IHC-P, E, Flo |
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Monoclonal CD247 / CD3 Zeta Antibody (clone 4A12-F6), Clone: 4A12-F6 |
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| AMM02065G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human CD247 / CD3 Zeta (clone 4A12-F6). The antibodies are raised in Mouse and are from clone 4A12-F6. This antibody is applicable in WB and IHC-P, E, IP |
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Monoclonal KLK3 / PSA Antibody (clone 1A7), Clone: 1A7 |
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| AMM04360G | Leading Biology | 0.05mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human KLK3 / PSA (clone 1A7). The antibodies are raised in Mouse-Balb/c and are from clone 1A7. This antibody is applicable in WB and IHC-P, ICC, IHC-Fr, ELISPOT, Flo |
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Monoclonal C/EBP Beta / CEBPB Antibody (aa39-78, clone 21A1), Clone: 21A1 |
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| AMM01710G | Leading Biology | 0.05mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human C/EBP Beta / CEBPB (aa39-78, clone 21A1). The antibodies are raised in Mouse and are from clone 21A1. This antibody is applicable in WB and IHC-P, IP |
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Monoclonal HDAC3 Antibody (aa224-428, clone 3A7B5), Clone: 3A7B5 |
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| AMM05319G | Leading Biology | 0.05ml | EUR 580.8 |
|
Description: A Monoclonal antibody against Human HDAC3 (aa224-428, clone 3A7B5). The antibodies are raised in Mouse and are from clone 3A7B5. This antibody is applicable in WB and IHC-P, E |
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Monoclonal CA3 / Carbonic Anhydrase III Antibody (clone 4A12-1A3), Clone: 4A12-1A3 |
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| AMM01982G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human CA3 / Carbonic Anhydrase III (clone 4A12-1A3). The antibodies are raised in Mouse and are from clone 4A12-1A3. This antibody is applicable in WB and IHC-P, E |
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Monoclonal NPRB / NPR2 Antibody (clone 2A6), Clone: 2A6 |
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| AMM06795G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human NPRB / NPR2 (clone 2A6). The antibodies are raised in Mouse and are from clone 2A6. This antibody is applicable in WB and IHC-P, E |
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Monoclonal GAX / MEOX2 Antibody (clone 6A5), Clone: 6A5 |
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| APC00051G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human GAX / MEOX2 (clone 6A5). The antibodies are raised in Mouse and are from clone 6A5. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal LRP1 / CD91 Antibody (clone 5A6), Clone: 5A6 |
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| APR08270G | Leading Biology | 0.05mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human LRP1 / CD91 (clone 5A6). The antibodies are raised in Mouse and are from clone 5A6. This antibody is applicable in WB and IHC-P, Flo |
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Monoclonal GOK / STIM1 Antibody (clone 5A2), Clone: 5A2 |
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| AMM05164G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human GOK / STIM1 (clone 5A2). The antibodies are raised in Mouse and are from clone 5A2. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal IRAK1 / IRAK Antibody (clone 3A9), Clone: 3A9 |
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| AMM01917G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human IRAK1 / IRAK (clone 3A9). The antibodies are raised in Mouse and are from clone 3A9. This antibody is applicable in WB and IHC-P, IF, E, IP, RNAi |
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Monoclonal AML1 / RUNX1 Antibody (clone 3A8), Clone: 3A8 |
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| AMM01983G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human AML1 / RUNX1 (clone 3A8). The antibodies are raised in Mouse and are from clone 3A8. This antibody is applicable in IHC-P, IF, E |
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Monoclonal AML1 / RUNX1 Antibody (clone 3A1), Clone: 3A1 |
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| AMM01984G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human AML1 / RUNX1 (clone 3A1). The antibodies are raised in Mouse and are from clone 3A1. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal LIMK1 / LIMK Antibody (clone 1A8), Clone: 1A8 |
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| AMM01996G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human LIMK1 / LIMK (clone 1A8). The antibodies are raised in Mouse and are from clone 1A8. This antibody is applicable in WB and IHC-P, E |
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Monoclonal APEX1 / APE1 Antibody (clone 2A4), Clone: 2A4 |
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| AMM02289G | Leading Biology | 0.05ml | EUR 580.8 |
|
Description: A Monoclonal antibody against Human APEX1 / APE1 (clone 2A4). The antibodies are raised in Mouse and are from clone 2A4. This antibody is applicable in WB and IHC-P, IF, Flo |
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Monoclonal PTPN22 / PEP Antibody (clone 1A6), Clone: 1A6 |
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| AMM07399G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human PTPN22 / PEP (clone 1A6). The antibodies are raised in Mouse and are from clone 1A6. This antibody is applicable in WB and IHC-P, E |
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Monoclonal FRK Antibody (clone 1A8H2C12), Clone: 1A8H2C12 |
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| AMM01872G | Leading Biology | 0.05ml | EUR 580.8 |
|
Description: A Monoclonal antibody against Human FRK (clone 1A8H2C12). The antibodies are raised in Mouse and are from clone 1A8H2C12. This antibody is applicable in WB and IHC-P, E |
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Metabolism and Toxicity of Emodin: Genome-Vast Affiliation Research Reveal Hepatocyte Nuclear Issue 4α Regulates UGT2B7 and Emodin Glucuronidation
- Emodin is the primary poisonous element in Chinese language medicinal herbs similar to rhubarb. Our earlier research demonstrated that genetic polymorphisms of UDP-glucuronosyltransferase 2B7 (UGT2B7) had an impact on the glucuronidation and detoxing of emodin.
- This research aimed to disclose the transcriptional regulation mechanism of UGT2B7 on emodin glucuronidation and its impact on toxicity. Emodin glucuronic exercise and genome and transcriptome information have been obtained from 36 medical human kidney tissues.
- The genome-wide affiliation research (GWAS) recognized that 4 single nucleotide polymorphisms (SNPs) (rs6093966, rs2868094, rs2071197, and rs6073433), which have been situated on the hepatocyte nuclear issue 4α (HNF4A) gene, have been considerably related to the emodin glucuronidation (p < 0.05). Notably, rs2071197 was considerably related to the gene expression of HNF4A and UGT2B7 and the glucuronidation of emodin.
Monoclonal EDEM2 Antibody (clone 2E4), Clone: 2E4
- The gene expression of HNF4A confirmed a excessive correlation with UGT2B7 (R2 = 0.721, p = 5.83 × 10-11). The luciferase exercise was elevated 7.68-fold in 293T cells and a pair of.03-fold in HepG2 cells, confirming a major transcriptional activation of UGT2B7 promoter by HNF4A.
- The knockdown of HNF4A in HepG2 cells (36.6%) led to a major lower of UGT2B7 (19.8%) and better cytotoxicity (p < 0.05).
- The overexpression of HNF4A in HepG2 cells (31.2%) led to a major enhance of UGT2B7 (24.4%) and improved cell viability (p < 0.05). Apart from, HNF4A and UGT2B7 have been each decreased in HepG2 cells and rats after remedy with emodin.
- In conclusion, emodin used long run or in excessive doses might inhibit the expression of HNF4A, thereby lowering the expression of UGT2B7 and inflicting hepatotoxicity.
Monoclonal THTPA Antibody (monoclonal) (M01), Clone: 3F6 |
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| APR10463G | Leading Biology | 0.1mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human THTPA (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3F6. This antibody is applicable in WB and IHC, E |
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Monoclonal TRAF4 Antibody (monoclonal) (M01), Clone: 3F6 |
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| AMM04241G | Leading Biology | 0.1mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human TRAF4 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3F6. This antibody is applicable in WB and IHC, E |
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Monoclonal PPARBP Antibody (monoclonal) (M06), Clone: 3F6 |
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| AMR09453G | Leading Biology | 0.1mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human PPARBP (monoclonal) (M06). The antibodies are raised in mouse and are from clone 3F6. This antibody is applicable in WB, E |
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Monoclonal BDKRB2 Antibody (monoclonal) (M01), Clone: 3F6 |
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| AMM03285G | Leading Biology | 0.1mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human BDKRB2 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3F6. This antibody is applicable in WB, E |
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Monoclonal SLC26A2 Antibody (monoclonal) (M04), Clone: 3F6 |
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| AMM07857G | Leading Biology | 0.1mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human SLC26A2 (monoclonal) (M04). The antibodies are raised in mouse and are from clone 3F6. This antibody is applicable in WB, E |
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Monoclonal ITGB3BP Antibody (monoclonal) (M01), Clone: 3F6 |
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| APR16922G | Leading Biology | 0.1mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human ITGB3BP (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3F6. This antibody is applicable in WB and IF, E |
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Monoclonal HIP1 Antibody (clone 1F12), Clone: 1F12 |
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| APR12372G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human HIP1 (clone 1F12). The antibodies are raised in Mouse and are from clone 1F12. This antibody is applicable in WB and IHC-P, E, IP |
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Monoclonal SOX9 Antibody (clone 3F11), Clone: 3F11 |
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| APR13497G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human SOX9 (clone 3F11). The antibodies are raised in Mouse and are from clone 3F11. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal GGA1 Antibody (clone 3F11), Clone: 3F11 |
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| APR16128G | Leading Biology | 0.05mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human GGA1 (clone 3F11). The antibodies are raised in Mouse and are from clone 3F11. This antibody is applicable in WB and IHC-P, E |
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Monoclonal IDH2 Antibody (clone 5F11), Clone: 5F11 |
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| APR07925G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human IDH2 (clone 5F11). The antibodies are raised in Mouse and are from clone 5F11. This antibody is applicable in WB and IHC-P, E |
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Monoclonal HIPK2 Antibody (clone 1F10), Clone: 1F10 |
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| AMM02007G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human HIPK2 (clone 1F10). The antibodies are raised in Mouse and are from clone 1F10. This antibody is applicable in WB and IHC-P, E |
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Monoclonal BMPR2 Antibody (clone 1F12), Clone: 1F12 |
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| AMM02275G | Leading Biology | 0.05ml | EUR 580.8 |
|
Description: A Monoclonal antibody against Human BMPR2 (clone 1F12). The antibodies are raised in Mouse and are from clone 1F12. This antibody is applicable in WB and IHC-P, E |
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Monoclonal STK33 Antibody (clone 3F10), Clone: 3F10 |
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| AMM08027G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human STK33 (clone 3F10). The antibodies are raised in Mouse and are from clone 3F10. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal CDKL1 Antibody (clone 1F12), Clone: 1F12 |
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| APR15374G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human CDKL1 (clone 1F12). The antibodies are raised in Mouse and are from clone 1F12. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal GSTA3 Antibody (clone 1F11), Clone: 1F11 |
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| AMM05234G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human GSTA3 (clone 1F11). The antibodies are raised in Mouse and are from clone 1F11. This antibody is applicable in WB and IHC-P, E |
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Monoclonal PODXL Antibody [Clone 4F10], Clone: 4F10 |
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| AMM00051G | Leading Biology | 0.1mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human PODXL [Clone 4F10]. The antibodies are raised in Mouse and are from clone 4F10. This antibody is applicable in WB, IHC and IF, FC, IP |
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Monoclonal CDC25C Antibody (clone 1F12), Clone: 1F12 |
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| AMM01893G | Leading Biology | 0.05ml | EUR 580.8 |
|
Description: A Monoclonal antibody against Human CDC25C (clone 1F12). The antibodies are raised in Mouse and are from clone 1F12. This antibody is applicable in WB and IHC-P, E |
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Monoclonal FAM50A Antibody (clone 5F10), Clone: 5F10 |
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| AMM01932G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human FAM50A (clone 5F10). The antibodies are raised in Mouse and are from clone 5F10. This antibody is applicable in WB and IHC-P, E |
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Monoclonal BPIFA2 Antibody (clone 1F12), Clone: 1F12 |
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| AMM02213G | Leading Biology | 0.05mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human BPIFA2 (clone 1F12). The antibodies are raised in Mouse and are from clone 1F12. This antibody is applicable in WB, IHC and IF, ICC, E, Flo |
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Monoclonal TNNI2 Antibody (clone 2F12G2), Clone: 2F12G2 |
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| AMM08269G | Leading Biology | 0.05mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human TNNI2 (clone 2F12G2). The antibodies are raised in Mouse and are from clone 2F12G2. This antibody is applicable in WB and IHC-P, IF, ICC, E, Flo |
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Monoclonal YAP / YAP1 Antibody (clone 2F12), Clone: 2F12 |
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| AMM01937G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human YAP / YAP1 (clone 2F12). The antibodies are raised in Mouse and are from clone 2F12. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal FAC1 / BPTF Antibody (clone 2F10), Clone: 2F10 |
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| APR11891G | Leading Biology | 0.05ml | EUR 580.8 |
|
Description: A Monoclonal antibody against Human FAC1 / BPTF (clone 2F10). The antibodies are raised in Mouse and are from clone 2F10. This antibody is applicable in WB and IHC-P, E |
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Monoclonal CD59 Antibody (clone 1F5), Clone: 1F5 |
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| AMM01702G | Leading Biology | 0.05mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human CD59 (clone 1F5). The antibodies are raised in Mouse and are from clone 1F5. This antibody is applicable in IHC-P, Flo |
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Monoclonal MYL3 Antibody (clone 3F8), Clone: 3F8 |
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| AMM01878G | Leading Biology | 0.05ml | EUR 580.8 |
|
Description: A Monoclonal antibody against Human MYL3 (clone 3F8). The antibodies are raised in Mouse and are from clone 3F8. This antibody is applicable in WB and IHC-P, E |
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Monoclonal IRF4 Antibody (clone 2F2), Clone: 2F2 |
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| AMM01918G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human IRF4 (clone 2F2). The antibodies are raised in Mouse and are from clone 2F2. This antibody is applicable in WB and IHC-P, E |
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Monoclonal FGF1 Antibody (clone 1F9), Clone: 1F9 |
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| AMM01992G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human FGF1 (clone 1F9). The antibodies are raised in Mouse and are from clone 1F9. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal NEK2 Antibody (clone 2F6), Clone: 2F6 |
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| AMM02013G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human NEK2 (clone 2F6). The antibodies are raised in Mouse and are from clone 2F6. This antibody is applicable in WB and IHC-P, E, IP |
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Monoclonal OSR1 Antibody (clone 3F3), Clone: 3F3 |
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| AMM02049G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human OSR1 (clone 3F3). The antibodies are raised in Mouse and are from clone 3F3. This antibody is applicable in IHC-P, IF, E |
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Monoclonal RCC1 Antibody (clone 2F1), Clone: 2F1 |
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| AMM02066G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human RCC1 (clone 2F1). The antibodies are raised in Mouse and are from clone 2F1. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal MAP2 Antibody (clone 5F9), Clone: 5F9 |
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| APR12495G | Leading Biology | 0.05mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human MAP2 (clone 5F9). The antibodies are raised in Mouse and are from clone 5F9. This antibody is applicable in WB and IHC-P |
|||
Monoclonal PAX5 Antibody (clone 8F9), Clone: 8F9 |
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| APR12736G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human PAX5 (clone 8F9). The antibodies are raised in Mouse and are from clone 8F9. This antibody is applicable in WB and IHC-P, E |
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Monoclonal PDK2 Antibody (clone 5F8), Clone: 5F8 |
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| APR09005G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human PDK2 (clone 5F8). The antibodies are raised in Mouse and are from clone 5F8. This antibody is applicable in WB and IHC-P, E |
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Monoclonal EMX2 Antibody (clone 4F7), Clone: 4F7 |
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| APG03285G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human EMX2 (clone 4F7). The antibodies are raised in Mouse and are from clone 4F7. This antibody is applicable in IHC-P, E |
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Monoclonal ERBB3 / HER3 Antibody (clone 3F12), Clone: 3F12 |
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| AMM02071G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human ERBB3 / HER3 (clone 3F12). The antibodies are raised in Mouse and are from clone 3F12. This antibody is applicable in IHC-P, E |
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Monoclonal MKNK1 / MNK1 Antibody (clone 2F12), Clone: 2F12 |
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| APR17373G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human MKNK1 / MNK1 (clone 2F12). The antibodies are raised in Mouse and are from clone 2F12. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal CFLAR / FLIP Antibody (clone 2F12), Clone: 2F12 |
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| APG02539G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human CFLAR / FLIP (clone 2F12). The antibodies are raised in Mouse and are from clone 2F12. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal NR1D1 Antibody (clone 4F6), Clone: 4F6 |
|||
| AMM06804G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human NR1D1 (clone 4F6). The antibodies are raised in Mouse and are from clone 4F6. This antibody is applicable in WB and IHC-P, IF, E, RNAi |
|||
Monoclonal WNT5A Antibody (clone 6F2), Clone: 6F2 |
|||
| AMM01852G | Leading Biology | 0.05ml | EUR 580.8 |
|
Description: A Monoclonal antibody against Human WNT5A (clone 6F2). The antibodies are raised in Mouse and are from clone 6F2. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal CSE1L Antibody (clone 3F8), Clone: 3F8 |
|||
| AMM01913G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human CSE1L (clone 3F8). The antibodies are raised in Mouse and are from clone 3F8. This antibody is applicable in WB and IHC-P, IF, E |
|||
Monoclonal SMAD6 Antibody (clone 4F3), Clone: 4F3 |
|||
| AMM01920G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human SMAD6 (clone 4F3). The antibodies are raised in Mouse and are from clone 4F3. This antibody is applicable in WB and IHC-P, E |
|||
Monoclonal THOC6 Antibody (clone 1F6), Clone: 1F6 |
|||
| AMM01947G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human THOC6 (clone 1F6). The antibodies are raised in Mouse and are from clone 1F6. This antibody is applicable in WB and IHC-P, E |
|||
Monoclonal SP140 Antibody (clone 3F9), Clone: 3F9 |
|||
| AMM02067G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human SP140 (clone 3F9). The antibodies are raised in Mouse and are from clone 3F9. This antibody is applicable in IHC-P, E |
|||
Monoclonal STK38 Antibody (clone 6F1), Clone: 6F1 |
|||
| AMM02099G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human STK38 (clone 6F1). The antibodies are raised in Mouse and are from clone 6F1. This antibody is applicable in WB and IHC-P, E |
|||
Monoclonal LRCH4 Antibody (clone 1F8), Clone: 1F8 |
|||
| AMM02296G | Leading Biology | 0.05ml | EUR 580.8 |
|
Description: A Monoclonal antibody against Human LRCH4 (clone 1F8). The antibodies are raised in Mouse and are from clone 1F8. This antibody is applicable in WB and IHC-P |
|||
Monoclonal TOM20 Antibody (clone 4F3), Clone: 4F3 |
|||
| APR10504G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human TOM20 (clone 4F3). The antibodies are raised in Mouse and are from clone 4F3. This antibody is applicable in WB and IHC-P, IF, E |
|||
Monoclonal ABHD5 Antibody (clone 1F3), Clone: 1F3 |
|||
| APG01441G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human ABHD5 (clone 1F3). The antibodies are raised in Mouse and are from clone 1F3. This antibody is applicable in WB and IHC-P, E |
|||
Monoclonal ATP5E Antibody (clone 2F3), Clone: 2F3 |
|||
| APG02119G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human ATP5E (clone 2F3). The antibodies are raised in Mouse and are from clone 2F3. This antibody is applicable in WB and IHC-P, E |
|||
Monoclonal GSTA1 Antibody (clone 2F7), Clone: 2F7 |
|||
| AMM05231G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human GSTA1 (clone 2F7). The antibodies are raised in Mouse and are from clone 2F7. This antibody is applicable in WB and IHC-P, E |
|||
Monoclonal WDR77 / MEP50 Antibody (clone 3F10), Clone: 3F10 |
|||
| AMM08511G | Leading Biology | 0.05mg | EUR 633.6 |
|
Description: A Monoclonal antibody against Human WDR77 / MEP50 (clone 3F10). The antibodies are raised in Mouse and are from clone 3F10. This antibody is applicable in WB and IHC-P, E |
|||
Monoclonal RICTOR Antibody (clone 1F3), Clone: 1F3 |
|||
| AMM02116G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human RICTOR (clone 1F3). The antibodies are raised in Mouse and are from clone 1F3. This antibody is applicable in WB and IHC-P, E, IP |
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Monoclonal SAMHD1 Antibody (clone 3F5), Clone: 3F5 |
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| AMM02276G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human SAMHD1 (clone 3F5). The antibodies are raised in Mouse and are from clone 3F5. This antibody is applicable in WB and IHC-P, IF, Flo |
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Monoclonal STAT5A Antibody (clone 9F7), Clone: 9F7 |
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| APR10279G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human STAT5A (clone 9F7). The antibodies are raised in Mouse and are from clone 9F7. This antibody is applicable in WB and IHC-P, IF, Flo |
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Monoclonal CAMKK1 Antibody (clone 1F6), Clone: 1F6 |
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| APG03194G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human CAMKK1 (clone 1F6). The antibodies are raised in Mouse and are from clone 1F6. This antibody is applicable in WB and IHC-P, E |
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Monoclonal RNF144B Antibody (clone 4F1), Clone: 4F1 |
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| AMM01951G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human RNF144B (clone 4F1). The antibodies are raised in Mouse and are from clone 4F1. This antibody is applicable in WB and IHC-P, IF, E |
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Monoclonal PPP2R2B Antibody (clone 1F3), Clone: 1F3 |
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| APR12943G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human PPP2R2B (clone 1F3). The antibodies are raised in Mouse and are from clone 1F3. This antibody is applicable in WB and IHC-P, E, IP |
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Monoclonal ERBB3 / HER3 Antibody (clone 3F10F6), Clone: 3F10F6 |
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| AMM01860G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human ERBB3 / HER3 (clone 3F10F6). The antibodies are raised in Mouse and are from clone 3F10F6. This antibody is applicable in WB and IHC-P, E |
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Monoclonal NF-L / NEFL Antibody (clone 2F11), Clone: 2F11 |
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| AMM06667G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human NF-L / NEFL (clone 2F11). The antibodies are raised in Mouse and are from clone 2F11. This antibody is applicable in WB and IHC-P, IHC-Fr |
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Monoclonal ALCAM / CD166 Antibody (clone 10F1G12), Clone: 10F1G12 |
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| AMM01858G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human ALCAM / CD166 (clone 10F1G12). The antibodies are raised in Mouse and are from clone 10F1G12. This antibody is applicable in IHC-P, E |
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Monoclonal p66 / SHC Antibody (clone 3F4), Clone: 3F4 |
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| APR12685G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human p66 / SHC (clone 3F4). The antibodies are raised in Mouse and are from clone 3F4. This antibody is applicable in WB and IHC-P, IF, E, PLA |
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Monoclonal MTDH / Metadherin Antibody (clone 2F11C3), Clone: 2F11C3 |
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| AMM01881G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human MTDH / Metadherin (clone 2F11C3). The antibodies are raised in Mouse and are from clone 2F11C3. This antibody is applicable in WB and IHC-P, E, Flo |
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Monoclonal HHEX / HEX Antibody (clone 3F4), Clone: 3F4 |
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| AMM02302G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human HHEX / HEX (clone 3F4). The antibodies are raised in Mouse and are from clone 3F4. This antibody is applicable in IHC-P, IF |
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Monoclonal GGT1 / GGT Antibody (clone 1F9), Clone: 1F9 |
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| AMR07733G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human GGT1 / GGT (clone 1F9). The antibodies are raised in Mouse and are from clone 1F9. This antibody is applicable in WB and IHC-P, E, IP |
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Monoclonal NTNG2 / Netrin G2 Antibody (clone 4F11), Clone: 4F11 |
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| AMM06850G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human NTNG2 / Netrin G2 (clone 4F11). The antibodies are raised in Mouse and are from clone 4F11. This antibody is applicable in WB and IHC-P, E |
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Monoclonal IMP-3 / IGF2BP3 Antibody (clone 8F11), Clone: 8F11 |
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| AMM02199G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human IMP-3 / IGF2BP3 (clone 8F11). The antibodies are raised in Mouse and are from clone 8F11. This antibody is applicable in WB and IHC-P, E |
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Monoclonal TIMP2 Antibody (clone F27P3A4), Clone: F27P3A4 |
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| AMM01705G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human TIMP2 (clone F27P3A4). The antibodies are raised in Mouse and are from clone F27P3A4. This antibody is applicable in WB and IHC-P, E |
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Monoclonal RICK / RIP2 Antibody (clone 7F5), Clone: 7F5 |
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| AMR09760G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human RICK / RIP2 (clone 7F5). The antibodies are raised in Mouse and are from clone 7F5. This antibody is applicable in WB, E, IHC-Fr |
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Monoclonal US01 / p115 Antibody (clone 3F4), Clone: 3F4 |
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| AMM08440G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human US01 / p115 (clone 3F4). The antibodies are raised in Mouse and are from clone 3F4. This antibody is applicable in WB and IHC-P, E |
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Monoclonal TSG / TWSG1 Antibody (clone 2F3), Clone: 2F3 |
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| APR13832G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human TSG / TWSG1 (clone 2F3). The antibodies are raised in Mouse and are from clone 2F3. This antibody is applicable in WB and IHC-P, E |
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Monoclonal CCK4 / PTK7 Antibody (clone 4F9), Clone: 4F9 |
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| APG02467G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human CCK4 / PTK7 (clone 4F9). The antibodies are raised in Mouse and are from clone 4F9. This antibody is applicable in WB and IHC-P, E |
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Monoclonal HNRNP-E2 / PCBP2 Antibody (clone 5F12), Clone: 5F12 |
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| AMM05385G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human HNRNP-E2 / PCBP2 (clone 5F12). The antibodies are raised in Mouse and are from clone 5F12. This antibody is applicable in WB and IHC-P, IF, E, RNAi |
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Monoclonal IRAK1 / IRAK Antibody (clone 3F7), Clone: 3F7 |
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| AMM01916G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A Monoclonal antibody against Human IRAK1 / IRAK (clone 3F7). The antibodies are raised in Mouse and are from clone 3F7. This antibody is applicable in WB and IHC-P, IF, E |
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