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Protective Effect of NADPH Oxidase Nuclear factor 

nfkb-p65
Posted by Nicole

Protecting impact of resveratrol on estrogen deficiency-induced osteoporosis although attenuating NADPH oxidase 4/nuclear issue kappa B pathway by growing miR-92b-3p expression

 

Introduction: Resveratrol (RES) reveals estrogen-like results and has potential functions to therapy of osteoporosis attributable to estrogen deficiency; nonetheless, the precise mechanism of motion of RES stays unclear. Right here, we examined the therapeutic results of RES on ovariectomized (OVX) rats with osteoporosis and decided the underlying mechanism.
Strategies: We established an OVX rat mannequin to check osteoporosis attributable to estrogen deficiency. The therapy teams got orally with RES (50, 100, and 200 mg/day), the estrogen group acquired 0.Eight mg/kg E2 every day through oral route, and the sham-operated and management teams acquired an equal dose of sodium carboxymethylcellulose orally. After 12 weeks of therapy, we used real-time quantitative polymerase chain response (PCR) and Western blot evaluation to measure the gene and protein expression of miR-92b-3p, Nox4, NF-κBp65, IκB, BMP2, Smad7, and RUNX-2 in bone tissues.

Cytochrome P450 4A11 (CYP4A11) Antibody

Proper femur structural parameters had been evaluated by micro-CT. Twin-energy X-ray 4500 W was used to find out systemic bone mineral density (BMD). Enzyme-linked immunosorbent assay (ELISA) kits had been used to find out the serum ranges of bone alkaline phosphatase (BALP), osteoprotegerin (OPG), anti-tartrate acid phosphatase-5b (PTRA5b), and carboxylated terminal peptide (CTX-I). The rat femoral bone specimens had been stained utilizing hematoxylin and eosin for pathological examination.
nfkb-p65
nfkb-p65
Outcomes: We noticed elevated ranges of serum estrogen in each ovaries, elevated miR-92b-3p ranges in bone tissues, lowered ranges of Nox4, NF-κBp65, p-IκB-a, and cathepsin Ok, and elevated gene and protein expression of BMP2, Smad7, and RUNX-2 within the OVX rat mannequin of osteoporosis after therapy with RES.
Elevated ranges of BALP, OPG, ALP, and BMD together with lowered ranges of TRAP-5b and CTX-I had been additionally noticed. The structural mannequin index (SMI) and the trabecular area (Tb. Sp) decreased, whereas the trabecular thickness (Tb. Th), bone quantity fraction (BV/TV), trabecular quantity (Tb.N), and tissue bone density (Conn.D) elevated, thereby bettering osteoporosis induced by estrogen deficiency in each ovaries.
Conclusion: Cathepsin Ok expression and Nox4/NF-κB signaling pathway had been suppressed by the elevated expression of miR-92b-3p. This inhibition was pivotal within the protecting impact of RES towards osteoporosis induced by estrogen deficiency in each ovaries. Thus, RES effectively alleviated osteoporosis induced by estrogen deficiency in rats.
Key phrases: NF-κBp65; Nox4; miR-92b-3p; osteoporosis; resveratrol.

 

 

 

Efficacy of inexperienced tea, its polyphenols and nanoformulation in experimental colitis and the function of non-canonical and canonical nuclear issue kappa beta (NF-kB) pathway: a preclinical in-vivo and in-silico exploratory examine

NF-kB performs a serious function within the aetiopathogenesis of inflammatory-colitis. On this examine, we evaluated the efficacy of inexperienced tea and its polyphenols and their nanoformulation in Tri-Nitro Benzene Sulfonic acid (TNBS) induced colitis in in-vivo system (Rat) and the involvement of non-canonical and canonical NF-kB pathway in inexperienced tea mediated safety (in-silico platform).

We used the Wister rat mannequin of TNBS-induced colitis. Rats had been grouped into eleven teams (six animals every) and administered car (ethanol), TNBS, Epicatechin (EC), Epigallocatechin (EGC), Epicatechin-gallate (ECG), Epigallocatechin-gallate (EGCG), sulfasalazine, inexperienced tea, EGCG + sulfasalazine, nano-EGCG and nano-EGCG + sulfasalazine for 14 days after induction of colitis.

Cytochrome P450 4A11 / 22 Blocking Peptide

Colonic tissue was evaluated for the extent of malondialdehyde, myeloperoxidase exercise, catalase, lowered glutathione, glutathione peroxidase, IL-6, TNF-α, IL-1β, NF-κB and morphological and histopathological proof of harm. Within the in-silico half, molecular docking and dynamic simulation examine of EGCG was accomplished towards totally different targets in NF-kB for detailed analysis of the function of non-canonical and canonical NF-KB pathway.

In our examine, EGCG lowered colonic irritation, markers of oxidative stress, TNF-α, NF-κB, IL-1β and IL-6. Nano-EGCG + sulfasalazine was extra efficacious when in comparison with EGCG + sulfasalazine. In molecular docking and molecular dynamic simulation research, EGCG confirmed a superb binding profile to the inhibitor binding websites of IKK-beta, IKK-alpha and NIK. Thus, it may be concluded that EGCG confirmed protecting motion in experimental colitis appearing by each non-canonical and canonical NF-kB pathway.

Nano-EGCG + sulfasalazine mixture confirmed higher safety than nano-EGCG alone. Communicated by Ramaswamy H. Sarma.

 

Monoclonal THUMPD1 Antibody (monoclonal) (M01), Clone: 4A11

AMM04196G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human THUMPD1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 4A11. This antibody is applicable in WB and IHC, E

Monoclonal PARVB Antibody (monoclonal) (M01), Clone: 4A11

APR17756G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human PARVB (monoclonal) (M01). The antibodies are raised in mouse and are from clone 4A11. This antibody is applicable in WB, E

anti-PDK1 (4A11)

LF-MA30516 100 ul
EUR 527
Description: Mouse Monoclonal to PDK1

anti-DLL4 (4A11)

LF-MA30736 100 ul
EUR 527
Description: Mouse Monoclonal to DLL4

anti-DLL4 (4A11)

LF-MA30749 100 ul
EUR 527
Description: Mouse Monoclonal to DLL4

TIGIT Antibody [4A11]

RF16055-002mg 0.02 mg
EUR 191.42
Description: TIGIT Antibody: The T cell immunoreceptor with Ig and ITIM domains (TIGIT) is a member of the PVR (poliovirus receptor) family of immunoglobin proteins. It is expressed on several classes of T cells including follicular B helper T cells (TFH). TIGIT has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses (1). Similar to other immune checkpoint proteins such as PD-1, TIGIT is upregulated on exhausted T cells in chronic viral infections and cancer. Blockade of both TIGIT and PD-1 pathways leads to tumor rejection in mice suggesting that it may be of therapeutic use against cancer (2).

TIGIT Antibody [4A11]

RF16055-01mg 0.1 mg
EUR 495.22
Description: TIGIT Antibody: The T cell immunoreceptor with Ig and ITIM domains (TIGIT) is a member of the PVR (poliovirus receptor) family of immunoglobin proteins. It is expressed on several classes of T cells including follicular B helper T cells (TFH). TIGIT has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses (1). Similar to other immune checkpoint proteins such as PD-1, TIGIT is upregulated on exhausted T cells in chronic viral infections and cancer. Blockade of both TIGIT and PD-1 pathways leads to tumor rejection in mice suggesting that it may be of therapeutic use against cancer (2).

Anti-PARVB (4A11)

YF-MA11471 100 ug
EUR 363
Description: Mouse monoclonal to PARVB

Anti-THUMPD1 (4A11)

YF-MA11563 100 ug
EUR 363
Description: Mouse monoclonal to THUMPD1

Anti-MAP1 (4A11)

YF-MA19202 100 ug
EUR 363
Description: Mouse monoclonal to MAP1

Anti-CaMKK (4A11)

YF-MA19533 100 ug
EUR 363
Description: Mouse monoclonal to CaMKK

Anti-LHX4 (4A11)

YF-MA19614 100 ug
EUR 363
Description: Mouse monoclonal to LHX4

Anti-CNKSR3 (4A11)

YF-MA19966 100 ug
EUR 363
Description: Mouse monoclonal to CNKSR3

Anti-FOXK2 (4A11)

YF-MA20345 100 ug
EUR 363
Description: Mouse monoclonal to FOXK2

Anti-CRLF2 (4A11)

YF-MA11626 100 ug
EUR 363
Description: Mouse monoclonal to CRLF2

Anti-JNK1 (4A11)

YF-MA14911 100 ug
EUR 363
Description: Mouse monoclonal to JNK1

Anti-APRIL (4A11)

YF-MA16500 100 ug
EUR 363
Description: Mouse monoclonal to APRIL

Anti-SSX3 (4A11)

YF-MA17194 100 ug
EUR 363
Description: Mouse monoclonal to SSX3

Cytochrome P450 4A11 antibody

22646-100ul 100ul
EUR 390

Cytochrome P450 4A11 antibody

70R-12729 100 ul
EUR 457
Description: Affinity purified Rabbit polyclonal Cytochrome P450 4A11 antibody

Anti-Hey L (4A11)

YF-MA18109 100 ug
EUR 363
Description: Mouse monoclonal to Hey L

Anti-Claudin 4 (4A11)

YF-MA12513 100 ug
EUR 363
Description: Mouse monoclonal to Claudin 4

Cytochrome P450 4A11/22 Antibody

35260-100ul 100ul
EUR 252

Cytochrome P450 4A11/22 Antibody

35260-50ul 50ul
EUR 187

Cytochrome P450 4A11 (CYP4A11) Antibody

20-abx111934
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Cytochrome P450 4A11 (CYP4A11) Antibody

20-abx320269
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul

Cytochrome P450 4A11 (CYP4A11) Antibody

20-abx339223
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Cytochrome P450 4A11 (CYP4A11) Antibody

20-abx006298
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Cytochrome P450 4A11 / 22 Antibody

20-abx009352
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

Cytochrome P450 4A11 (CYP4A11) Antibody

abx033743-400ul 400 ul
EUR 523

Cytochrome P450 4A11 (CYP4A11) Antibody

abx033743-80l 80 µl
EUR 286

Cytochrome P450 4A11 / 22 Antibody

20-abx015130
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Cytochrome P450 4A11 (CYP4A11) Antibody

20-abx213072
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Cytochrome P450 4A11 (CYP4A11) Antibody

abx232168-100ug 100 ug
EUR 509

Cytochrome P450 4A11/22 Antibody

DF4749 200ul
EUR 304
Description: Cytochrome P450 4A11/22 Antibody detects endogenous levels of total Cytochrome P450 4A11/22.

Cytochrome P450 4A11/22 Antibody

ABD13062 100 ug
EUR 438

Cytochrome P450 4A11/22 Antibody

ABD4749 100 ug
EUR 438

Cytochrome P450 4A11/22 antibody

70R-49642 100 ul
EUR 244
Description: Purified Polyclonal Cytochrome P450 4A11/22 antibody

Anti-Musashi 1 / Msi1 (4A11)

YF-MA10581 100 ug
EUR 363
Description: Mouse monoclonal to Musashi 1 / Msi1

Anti-NFkB p105 / p50 (4A11)

YF-MA10626 100 ug
EUR 363
Description: Mouse monoclonal to NFkB p105 / p50

Anti-Cyclin A1 (4A11-5B5)

YF-MA16598 100 ug
EUR 363
Description: Mouse monoclonal to Cyclin A1

Anti-Cytochrome P450 4A11/22 Antibody

A03493 100ul
EUR 397
Description: Rabbit Polyclonal Cytochrome P450 4A11/22 Antibody. Validated in WB and tested in Human.

Cytochrome P450 4A11 / 22 Blocking Peptide

20-abx062517
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg

Cytochrome P450 4A11/22 Conjugated Antibody

C35260 100ul
EUR 397

Cytochrome P450 4A11/22 Blocking Peptide

DF4749-BP 1mg
EUR 195

Human Cytochrome P450 4A11 (CYP4A11) ELISA Kit

abx386773-96tests 96 tests
EUR 911

Human Cytochrome P450 4A11, CYP4A11 ELISA KIT

ELI-31956h 96 Tests
EUR 824

Rat Cytochrome P450 4A11(CYP4A11) ELISA kit

E02C2253-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Cytochrome P450 4A11(CYP4A11) ELISA kit

E02C2253-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Cytochrome P450 4A11(CYP4A11) ELISA kit

E02C2253-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cytochrome P450 4A11(CYP4A11) ELISA kit

E09C2253-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Monkey Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cytochrome P450 4A11(CYP4A11) ELISA kit

E09C2253-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cytochrome P450 4A11(CYP4A11) ELISA kit

E09C2253-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Cytochrome P450 4A11(CYP4A11) ELISA kit

E08C2253-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Canine Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Cytochrome P450 4A11(CYP4A11) ELISA kit

E08C2253-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Canine Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Cytochrome P450 4A11(CYP4A11) ELISA kit

E08C2253-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Canine Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Cytochrome P450 4A11(CYP4A11) ELISA kit

E01C2253-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Human Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Cytochrome P450 4A11(CYP4A11) ELISA kit

E01C2253-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Human Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Cytochrome P450 4A11(CYP4A11) ELISA kit

E01C2253-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Human Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Cytochrome P450 4A11(CYP4A11) ELISA kit

E04C2253-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rabbit Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Cytochrome P450 4A11(CYP4A11) ELISA kit

E04C2253-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rabbit Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Cytochrome P450 4A11(CYP4A11) ELISA kit

E04C2253-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rabbit Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Cytochrome P450 4A11(CYP4A11) ELISA kit

E03C2253-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Cytochrome P450 4A11(CYP4A11) ELISA kit

E03C2253-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Cytochrome P450 4A11(CYP4A11) ELISA kit

E03C2253-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Cytochrome P450 4A11(CYP4A11) ELISA kit

E07C2253-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Porcine Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Cytochrome P450 4A11(CYP4A11) ELISA kit

E07C2253-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Porcine Cytochrome P450 4A11(CYP4A11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Gentiopicroside Ameliorates Oxidative Stress and Lipid Accumulation by Nuclear Issue Erythroid 2-Associated Issue 2 Activation

 

 

NFKB1 Antibody

1-CSB-PA003434
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/40000

NFKB1 Antibody

1-CSB-PA004763
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000

NFKB1 Antibody

1-CSB-PA10354A0Rb
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF, ChIP; Recommended dilution: WB:1:500-1:5000, IHC:1:100-1:500, IF:1:50-1:500

NFKB1 Antibody

1-CSB-PA020085
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

NFKB1 Antibody

1-CSB-PA020086
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/5000

NFKB1 Antibody

1-CSB-PA020090
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

NFKB1 Antibody

1-CSB-PA020096
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

NFKB1 Antibody

1-CSB-PA015759GA01HU
  • EUR 597.00
  • EUR 333.00
  • 150ul
  • 50ul
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB

NFKB1 Antibody

1-CSB-PA441503
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:1000-1:2000, WB:1:200-1:1000

NFKB1 Antibody

1-CSB-PA546304
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:500-1:5000, IHC:1:25-1:100

Kappa (NFKB1)

MO47031 100 ul
EUR 349

NFKB1 Antibody

35588-100ul 100ul
EUR 252

NFKB1 siRNA

20-abx925825
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

NFKB1 siRNA

20-abx925826
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

NFKB1 antibody

39087-100ul 100ul
EUR 252

NFKB1 Antibody

BF0466 200ul
EUR 376
Description: NFKB1 antibody detects endogenous levels of total NFKB1.

NFKB1 antibody

20-PR03 100 ul
EUR 569
Description: Rabbit polyclonal NFKB1 antibody

NFKB1 antibody

10R-11003 100 ug
EUR 349
Description: Mouse monoclonal NFKB1 antibody

NFKB1 antibody

10R-11155 100 ug
EUR 349
Description: Mouse Monoclonal NFKB1 antibody

NFKB1 antibody

70R-18860 50 ul
EUR 435
Description: Rabbit polyclonal NFKB1 antibody

NFKB1 antibody

70R-10525 50 ug
EUR 467
Description: Affinity purified rabbit polyclonal NFKB1 antibody

NFKB1 antibody

70R-15433 100 ug
EUR 327
Description: Rabbit polyclonal NFKB1 antibody

NFKB1 cloning plasmid

CSB-CL015759HU-10ug 10ug
EUR 924
Description: A cloning plasmid for the NFKB1 gene.

Anti-NFKB1 antibody

STJ28750 100 µl
EUR 413
Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.

Anti-NFKB1 antibody

STJ116954 100 µl
EUR 277
Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.

Anti-NFKB1 antibody

STJ113719 100 µl
EUR 277
Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.

NFKB1 (pS337) Antibody

20-abx000177
  • EUR 495.00
  • EUR 704.00
  • EUR 356.00
  • 100 ul
  • 200 ul
  • 50 ul

NFKB1 (pS927) Antibody

20-abx000315
  • EUR 495.00
  • EUR 704.00
  • EUR 356.00
  • 100 ul
  • 200 ul
  • 50 ul

NFKB1 (pS893) Antibody

20-abx000462
  • EUR 495.00
  • EUR 704.00
  • EUR 356.00
  • 100 ul
  • 200 ul
  • 50 ul

NFKB1 (pS907) Antibody

20-abx000463
  • EUR 495.00
  • EUR 704.00
  • EUR 356.00
  • 100 ul
  • 200 ul
  • 50 ul

NFKB1 (pS932) Antibody

20-abx000464
  • EUR 495.00
  • EUR 704.00
  • EUR 356.00
  • 100 ul
  • 200 ul
  • 50 ul

NFKB1 Rabbit pAb

A14754-100ul 100 ul
EUR 308

NFKB1 Rabbit pAb

A14754-200ul 200 ul
EUR 459

NFKB1 Rabbit pAb

A14754-20ul 20 ul
EUR 183

NFKB1 Rabbit pAb

A14754-50ul 50 ul
EUR 223

NFKB1 Rabbit pAb

A11160-100ul 100 ul
EUR 308

NFKB1 Rabbit pAb

A11160-200ul 200 ul
EUR 459

NFKB1 Rabbit pAb

A11160-20ul 20 ul
EUR 183

NFKB1 Rabbit pAb

A11160-50ul 50 ul
EUR 223

NFKB1 Polyclonal Antibody

A68309 100 µg
EUR 570.55
Description: kits suitable for this type of research

Anti-NFKB1 antibody

STJ99314 200 µl
EUR 197
Description: Mouse monoclonal to NFKB1.

NFKB1 Conjugated Antibody

C35588 100ul
EUR 397

NFKB1 Conjugated Antibody

C39087 100ul
EUR 397

anti- NFKB1 antibody

FNab05702 100µg
EUR 505.25
Description: Antibody raised against NFKB1

anti- NFKB1 antibody

FNab05703 100µg
EUR 585
Description: Antibody raised against NFKB1

anti- NFKB1 antibody

FNab10143 100µg
EUR 505.25
Description: Antibody raised against NFKB1

NFKB1 Blocking Peptide

BF0466-BP 1mg
EUR 195

anti-NFKB1 (5D10)

LF-MA30587 100 ul
EUR 527
Description: Mouse Monoclonal to NFKB1

anti-NFKB1 (5D10D11)

LF-MA30597 100 ul
EUR 527
Description: Mouse Monoclonal to NFKB1

NFKB1 Blocking Peptide

33R-5351 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of NFKB1 antibody, catalog no. 70R-10525

NFKB1 antibody (HRP)

60R-2109 100 ug
EUR 327
Description: Rabbit polyclonal NFKB1 antibody (HRP)

NFKB1 antibody (FITC)

60R-2110 100 ug
EUR 327
Description: Rabbit polyclonal NFKB1 antibody (FITC)

NFKB1 antibody (biotin)

60R-2111 100 ug
EUR 327
Description: Rabbit polyclonal NFKB1 antibody (biotin)

Anti-NFKB1 antibody

PAab05702 100 ug
EUR 355

Anti-NFKB1 antibody

PAab05703 100 ug
EUR 412

Phospho-NFKB1 (Ser927) Antibody

CSB-PA283590-
EUR 335
Description: A polyclonal antibody against Phospho-NFKB1 (Ser927). Recognizes Phospho-NFKB1 (Ser927) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

Phospho-NFKB1 (Ser927) Antibody

CSB-PA283590-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-NFKB1 (Ser927). Recognizes Phospho-NFKB1 (Ser927) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

Phospho-NFKB1 (Ser893) Antibody

CSB-PA258273-
EUR 335
Description: A polyclonal antibody against Phospho-NFKB1 (Ser893). Recognizes Phospho-NFKB1 (Ser893) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF;IHC:1:50-1:100, IF:1:100-1:200

Phospho-NFKB1 (Ser893) Antibody

CSB-PA258273-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-NFKB1 (Ser893). Recognizes Phospho-NFKB1 (Ser893) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF;IHC:1:50-1:100, IF:1:100-1:200

NFKB1 (Ab-337) Antibody

CSB-PA186775-
EUR 335
Description: A polyclonal antibody against NFKB1 (Ab-337). Recognizes NFKB1 (Ab-337) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

NFKB1 (Ab-337) Antibody

CSB-PA186775-100ul 100ul
EUR 316
Description: A polyclonal antibody against NFKB1 (Ab-337). Recognizes NFKB1 (Ab-337) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

NFKB1 (Ab-932) Antibody

CSB-PA190132-
EUR 335
Description: A polyclonal antibody against NFKB1 (Ab-932). Recognizes NFKB1 (Ab-932) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

NFKB1 (Ab-932) Antibody

CSB-PA190132-100ul 100ul
EUR 316
Description: A polyclonal antibody against NFKB1 (Ab-932). Recognizes NFKB1 (Ab-932) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

NFKB1 (Ab-907) Antibody

CSB-PA696291-
EUR 335
Description: A polyclonal antibody against NFKB1 (Ab-907). Recognizes NFKB1 (Ab-907) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

NFKB1 (Ab-907) Antibody

CSB-PA696291-100ul 100ul
EUR 316
Description: A polyclonal antibody against NFKB1 (Ab-907). Recognizes NFKB1 (Ab-907) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

Phospho-NFKB1 (S893) Antibody

1-CSB-PA000579
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Phospho-NFKB1 (S893). Recognizes Phospho-NFKB1 (S893) from Human. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

Phospho-NFKB1 (S907) Antibody

1-CSB-PA000580
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Phospho-NFKB1 (S907). Recognizes Phospho-NFKB1 (S907) from Human. This antibody is Unconjugated. Tested in the following application: WB, IHC, IP, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IP:2-5ug/mglysate.ELISA:1/20000

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